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\u7d50\u679c<\/strong><\/p>\n

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\u8a0e\u8ad6<\/strong><\/p>\n

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\u7f8e\u570b\u8457\u540d\u7684\u6885\u7d04\u8a3a\u6240(Mayo Clinic)\u65bc1999\u5e74\u63d0\u51fa\u4e00\u500b\u985b\u8986\u50b3\u7d71\u89c0\u5ff5\u7684\u5831\u544a(11)\uff0c\u6307\u51fa\u6162\u6027\u9f3b\u7ac7\u708e\u5f88\u53ef\u80fd\u662f\u8d77\u56e0\u65bc\u5c0d\u9ef4\u83cc\u7684\u4e00\u7a2e\u904e\u654f\u6027\u53cd\u61c9\uff0c\u800c\u4e0d\u662f\u7d30\u83cc\u611f\u67d3\uff0c\u6240\u4ee5\u6cbb\u7642\u7684\u65b9\u5411\u61c9\u8a72\u662f\u91dd\u5c0d\u9ef4\u83cc\u7684\u904e\u654f\u6027\u53cd\u61c9\u3002\u745e\u5178\u7684Ricchetti\u91ab\u5e2b\u5247\u6307\u51fa\u4f7f\u7528\u9632\u6cbb\u9ef4(Amphotericin)\u9023\u7e8c\u6c96\u6d17\u9f3b\u8154\u4e00\u500b\u6708\uff0c39%\u7684\u9f3b\u761c\u8089\u6703\u5b8c\u5168\u6d88\u5931(12)\u3002\u6240\u4ee5\u91dd\u5c0d\u4e00\u4e9b\u9ef4\u83cc\u6027\u9f3b\u7ac7\u708e\u3001\u9f3b\u761c\u8089\u7684\u60a3\u8005\uff0c\u4e5f\u53ef\u4ee5\u5148\u8003\u616e\u4f7f\u7528\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\u6dfb\u52a0\u9632\u6cbb\u9ef4\u6c96\u6d17\u4f86\u6cbb\u7642\uff0c\u5982\u679c\u75c7\u72c0\u6c92\u6539\u5584\uff0c\u518d\u8003\u616e\u624b\u8853\u6cbb\u7642\u3002<\/p>\n

\u5c0d\u65bc\u4e00\u822c\u7684\u6162\u6027\u9f3b\u7ac7\u708e\u60a3\u8005\uff0c\u6211\u5011\u5efa\u8b70\u4f7f\u7528\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\uff0c\u6bcf\u5929\u6c96\u6d172-4\u6b21.\u5982\u679c\u4f7f\u75282-4\u9031\u5f8c\uff0c\u75c7\u72c0\u4ecd\u672a\u898b\u6539\u5584\uff0c\u518d\u8003\u616e\u6dfb\u52a0\u6297\u751f\u7d20\u4f86\u6c96\u6d17\u3002\u56e0\u70ba\u5f88\u591a\u7684\u7814\u7a76\u5831\u544a\u6307\u51fa\uff0c\u55ae\u7d14\u7684\u6301\u7e8c\u4f7f\u7528\u9e7d\u6c34\u6c96\u6d17\u9f3b\u5b50\uff0c\u5c0d\u9f3b\u7ac7\u708e\u7684\u75c7\u72c0\u6539\u5584\u5f88\u6709\u5e6b\u52a9\u3002Hartog\u91ab\u5e2b\u7684\u7814\u7a76\u5c31\u6307\u51fa(13)\uff0c\u9023\u7e8c\u4f7f\u7528\u6d17\u9f3b\u5668\u6c96\u6d17\u9f3b\u5b50\u4e00\u5e74\uff0c58%\u7684\u9f3b\u7ac7\u708e\u60a3\u8005\u53ef\u4ee5\u4e0d\u9808\u63a5\u53d7\u624b\u8853\u6cbb\u7642\u3002Davidson\u91ab\u5e2b\u7684\u7814\u7a76\u5831\u544a\u4e5f\u6307\u51fa\uff0c\u6bcf\u5929\u65e9\u665a\u4f7f\u7528\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\uff0c\u9023\u7e8c6\u5468\uff0c76%\u7684\u9f3b\u708e\u60a3\u8005(\u5305\u62ec\u9f3b\u7ac7\u708e\u3001\u904e\u654f\u6027\u9f3b\u708e\u3001\u9f3b\u6d95\u5012\u6d41\u7b49)\u90fd\u6703\u6709\u660e\u986f\u7684\u9032\u6b65\u3002\u6211\u5011\u7684\u81e8\u5e8a\u89c0\u5bdf\u4e5f\u8b49\u5be6\uff0c\u5f88\u591a\u7684\u6025\u3001\u6162\u6027\u9f3b\u7ac7\u708e\u3001\u904e\u654f\u6027\u9f3b\u708e\u3001\u9f3b\u6d95\u5012\u6d41\u3001\u611f\u5192\u3001\u9f3b\u585e\u3001\u6d41\u9f3b\u6d95\u7b49\u60a3\u8005\uff0c\u5982\u679c\u7a4d\u6975\u6301\u7e8c\u7684\u4f7f\u7528\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\uff0c\u75c7\u72c0\u5f88\u591a\u90fd\u80fd\u7372\u5f97\u6539\u5584\u3002<\/p>\n

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\u800c\u5c0d\u65bc\u56e0\u70ba\u653e\u5c04\u7dda\u6cbb\u7642\u9f3b\u54bd\u764c\u6216\u5176\u4ed6\u982d\u9838\u90e8\u764c\u75c7\u6240\u7e8c\u767c\u7684\u9f3b\u7ac7\u708e\uff0c\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\u66f4\u662f\u6cbb\u7642\u7684\u9996\u9078\u3002\u56e0\u70ba\u9019\u7a2e\u653e\u5c04\u7dda\u6cbb\u7642\u5f15\u8d77\u7684\u9f3b\u7ac7\u708e\uff0c\u4e26\u4e0d\u50cf\u4e00\u822c\u611f\u5192\u7e8c\u767c\u7684\u9f3b\u7ac7\u708e\uff0c\u75c5\u56e0\u5728\u9f3b\u7ac7\u958b\u53e3\u7684\u5835\u585e\u816b\u8139\uff0c\u800c\u662f\u5728\u65bc\u9f3b\u7ac7\u5167\u7684\u9ecf\u6db2\u7e96\u6bdb\u6e05\u9664\u529f\u80fd\u906d\u53d7\u653e\u5c04\u7dda\u7684\u7834\u58de\u3002\u4e00\u65b9\u9762\u9f3b\u9ecf\u6db2\u5206\u6ccc\u91cf\u6e1b\u5c11\uff0c\u4f7f\u5f97\u9f3b\u9ecf\u6db2\u8b8a\u81bf\u7a20\uff1b\u53e6\u4e00\u65b9\u9762\uff0c\u9f3b\u7ac7\u7121\u6cd5\u6709\u6548\u7684\u5c07\u6b64\u5206\u6ccc\u7269\u85c9\u52a9\u6b63\u5e38\u7684\u9ecf\u6db2\u7e96\u6bdb\u6e05\u9664\u529f\u80fd\uff0c\u7d93\u7531\u9f3b\u8154\u3001\u9f3b\u54bd\u90e8\u3001\u5589\u56a8\u5230\u80c3\u4e2d\u5206\u89e3\u6389\u3002\u6240\u4ee5\u624b\u8853\u6cbb\u7642\u5c0d\u653e\u5c04\u7dda\u9f3b\u7ac7\u708e\u7684\u6cbb\u7642\u6548\u679c\u4e26\u4e0d\u597d(15)\uff0c\u56e0\u70ba\u5b83\u7121\u6cd5\u6539\u5584\u9ecf\u6db2\u7e96\u6bdb\u6e05\u9664\u529f\u80fd\uff1b\u800c\u53e3\u670d\u6297\u751f\u7d20\u4e5f\u4e0d\u6613\u9577\u671f\u670d\u7528\uff0c\u7d93\u5e38\u662f\u5403\u5403\u505c\u505c\uff0c\u5f88\u5bb9\u6613\u7522\u751f\u6297\u85e5\u6027\u3002\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\u5247\u53ef\u85c9\u52a9\u5176\u985e\u4f3c\u7e96\u6bdb\u904b\u52d5\u7684\u8108\u52d5\u5f0f\u6c34\u7642\u6309\u6469\uff0c\u5354\u52a9\u6e05\u9664\u9f3b\u7ac7\u5167\u7684\u5206\u6ccc\u7269\uff0c\u540c\u6642\u8b93\u9ecf\u6db2\u7e96\u6bdb\u6e05\u9664\u529f\u80fd\u6162\u6162\u6062\u5fa9\u3002\u52a0\u4e0a\u5176\u64cd\u4f5c\u7c21\u55ae\uff0c\u60a3\u8005\u53ef\u5728\u5bb6\u81ea\u884c\u4f7f\u7528\uff0c\u9577\u671f\u4f7f\u7528\u8cbb\u7528\u4f4e\u5ec9\uff0c\u53c8\u7121\u660e\u986f\u526f\u4f5c\u7528\uff0c\u662f\u975e\u5e38\u503c\u5f97\u63a8\u5ee3\u7684\u4e00\u7a2e\u4fdd\u5065\u7642\u6cd5\u3002<\/p>\n

\u800c\u5728\u6c96\u6d17\u6eb6\u6db2\u90e8\u5206\uff0c\u6211\u5011\u63a8\u85a6\u4f7f\u7528\u4e0d\u542b\u7898\u7684\u98df\u7528\u9ad8\u7d1a\u7cbe\u9e7d(1000cc\u7684\u6eab\u6c34\u4e2d\u6dfb\u52a09\u516c\u514b\u7684\u9e7d)\uff0c\u6216\u8005\u5728\u9e7d\u4e2d\u6dfb\u52a0\u70d8\u57f9\u7528\u5c0f\u8607\u6253(1000cc\u7684\u6eab\u6c34\u4e2d\u6dfb\u52a06\u516c\u514b\u7684\u9e7d\u548c3\u516c\u514b\u7684\u5c0f\u8607\u6253)\u3002\u5169\u8005\u4f7f\u7528\u6548\u679c\u5dee\u4e0d\u591a(16)\uff0c\u4f46\u662f\u6dfb\u52a0\u5c0f\u8607\u6253\u7684\u4e2d\u548c\u9e7d(buffered saline)\u4f7f\u7528\u4e4b\u611f\u89ba\u8f03\u8212\u670d\u3002\u5982\u679c\u60a3\u8005\u53ef\u4ee5\u63a5\u53d7\u7684\u8a71\uff0c\u4e5f\u53ef\u4ee5\u5617\u8a66\u4f7f\u7528\u9ad8\u6fc3\u5ea6\u7684\u9e7d\u4f86\u6c96\u6d17\u3002\u6839\u64da\u6211\u5011\u7684\u81e8\u5e8a\u7d93\u9a57\uff0c\u4e00\u822c\u6210\u5e74\u4eba\u53ef\u4ee5\u5fcd\u53d72-3\u500d\u6fc3\u5ea6\u7684\u9e7d\u6c34\u6c96\u6d17\uff0c\u5c0f\u5b69\u5247\u901a\u5e38\u53ea\u80fd\u5fcd\u53d71.5-2\u500d\u6fc3\u5ea6\u7684\u9e7d\u6c34\u6c96\u6d17\u3002\u5f88\u591a\u7684\u7814\u7a76\u5747\u6307\u51fa\uff0c\u4f7f\u7528\u9ad8\u6fc3\u5ea6\u9e7d\u6c34\u6c96\u6d17\uff0c\u5c0d\u9f3b\u7ac7\u708e\u7684\u6548\u679c\u6bd4\u751f\u7406\u98df\u9e7d\u6c34\u4f86\u7684\u597d(17,18)\uff0c\u672c\u4eba\u7684\u81e8\u5e8a\u89c0\u5bdf\u4e5f\u8b49\u5be6\u9ad8\u6fc3\u5ea6\u9e7d\u6c34\u6c96\u6d17\u5c0d\u9f3b\u7ac7\u708e\u7684\u6548\u679c\u8f03\u597d\u3002\u81f3\u65bc\u5e02\u9762\u4e0a\u8ca9\u552e\u6d17\u9f3b\u5c08\u7528\u7684\u6d77\u9e7d\u6216\u6eab\u6cc9\u9e7d\uff0c\u500b\u4eba\u5247\u6301\u4fdd\u7559\u7684\u614b\u5ea6\uff0c\u56e0\u70ba\u5f88\u591a\u6b50\u6d32\u7684\u91ab\u5b78\u7814\u7a76\u5831\u544a\u90fd\u6307\u51fa(19,20)\uff0c\u6d77\u9e7d\u6c96\u6d17\u7684\u6548\u679c\u4e26\u4e0d\u6703\u6bd4\u751f\u7406\u98df\u9e7d\u6c34\u597d\uff0c\u800c\u4e14\u50f9\u683c\u6602\u8cb4\uff0c\u4e0d\u9069\u5408\u5927\u91cf\u4f7f\u7528\u3002\u540c\u6642\u7f8e\u570b\u6709\u4e9b\u8033\u9f3b\u5589\u79d1\u91ab\u5e2b\u5c0d\u65bc\u6b64\u6d77\u9e7d\u662f\u5426\u80fd\u5c07\u6d77\u6c34\u4e2d\u6d77\u6d0b\u751f\u7269\u7684\u6b98\u9ab8\u6216\u6392\u6cc4\u7269\u5b8c\u5168\u6e05\u9664\u4e7e\u6de8\uff0c\u4e5f\u6301\u4fdd\u7559\u7684\u614b\u5ea6\u3002<\/p>\n

\u5728\u6c96\u6d17\u6eb6\u6db2\u7684\u6eab\u5ea6\u65b9\u9762\uff0c\u5efa\u8b70\u4f7f\u7528\u63a5\u8fd1\u9ad4\u6eab\u768435-38\u2103\u4e4b\u9593\uff0c\u5118\u91cf\u4e0d\u8981\u4f7f\u7528\u51b7\u6c34\u6c96\u6d17\u3002\u4f7f\u7528\u51b7\u6c34\u6c96\u6d17\uff0c\u53ef\u80fd\u6703\u4f7f\u9f3b\u8154\u9ecf\u819c\u816b\u8139\uff0c\u540c\u6642\u9084\u6703\u5f71\u97ff\u9f3b\u8154\u9f3b\u7ac7\u5167\u7684\u7e96\u6bdb\u904b\u52d5;\u800c\u4e14\u611f\u89ba\u4e0d\u8212\u670d\u3002
\n\u7d50\u8ad6<\/p>\n

\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\u85c9\u52a9\u5176\u63d0\u4f9b\u8207\u9f3b\u8154\u53ca\u9f3b\u7ac7\u4e0a\u9ecf\u819c\u4e4b\u9ecf\u6db2\u7e96\u6bdb\u904b\u52d5\u8fd1\u4f3c\u983b\u7387\u7684\u6c34\u7642\u8108\u52d5\uff0c\u6709\u6548\u7684\u6e05\u9664\u9f3b\u7ac7\u5167\u4e4b\u81bf\u7a20\u5206\u6ccc\u7269\u4ee5\u53ca\u4fc3\u9032\u9ecf\u6db2\u7e96\u6bdb\u904b\u52d5\uff0c\u5c0d\u65bc\u9f3b\u7ac7\u708e\u7684\u6cbb\u7642\u5f88\u6709\u5e6b\u52a9\u3002\u76f8\u8f03\u65bc\u9f3b\u7ac7\u708e\u5176\u4ed6\u7684\u6cbb\u7642\u65b9\u5f0f\u800c\u8a00\uff0c\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\u4e4b\u64cd\u4f5c\u7c21\u55ae\ufe51\u65b9\u4fbf\ufe51\u7bc0\u7701\u60a3\u8005\u7684\u6642\u9593\u4ee5\u53ca\u91ab\u7642\u6210\u672c\uff0c\u800c\u4e14\u5b89\u5168\u6027\u9ad8\uff0c\u5f88\u5c11\u526f\u4f5c\u7528\u3002\u540c\u6642\u6700\u91cd\u8981\u7684\u662f\uff0c\u5982\u679c\u9f3b\u7ac7\u708e\u5fa9\u767c\uff0c\u76f8\u5c0d\u65bc\u5176\u4ed6\u6cbb\u7642\u6cd5\uff0c\u60a3\u8005\u7684\u518d\u4f7f\u7528\u7387\u53ca\u63a5\u53d7\u5ea6\u975e\u5e38\u9ad8\u3002\u800c\u5c0d\u65bc\u63a5\u53d7\u5404\u7a2e\u9f3b\u708e\u624b\u8853\u7684\u60a3\u8005\uff0c\u8853\u5f8c\u4f7f\u7528\u8108\u52d5\u5f0f\u9f3b\u8154\u6eab\u9e7d\u6c34\u7642\u6cd5\u5c0d\u50b7\u53e3\u7684\u6062\u5fa9\u6709\u5f88\u5927\u7684\u5e6b\u52a9\uff0c\u4e5f\u53ef\u5927\u5e45\u6e1b\u5c11\u6297\u751f\u7d20\u7684\u4f7f\u7528\uff0c\u4ee5\u53ca\u6e1b\u5c11\u91ab\u7642\u8cc7\u6e90\u7684\u6d6a\u8cbb\uff0c\u662f\u4e00\u7a2e\u975e\u5e38\u503c\u5f97\u63a8\u5ee3\u7684\u9f3b\u8154\u4fdd\u5065\u6cbb\u7642\u65b9\u6cd5\u3002(\u611f\u8b1d\u8108\u52d5\u5f0f\u6d17\u9f3b\u5668\u539f\u5275\u4eba\u7f8e\u570bMurray Grossan\u91ab\u5e2b\u4e4b\u6307\u5c0e)<\/p>\n

\u8868\u4e00 \u9f3b\u7ac7\u708e\u4e4b\u81e8\u5e8a\u75c7\u72c0\u7d00\u9304<\/p>\n

\u6253\u5674\u568f\uff0c\u6d41\u9f3b\u6c34\uff0c\u9f3b\u585e\uff0c\u81bf\u7a20\u9f3b\u6d95\uff0c\u9f3b\u6d95\u5012\u6d41\uff0c\u9f3b\u5b50\u81ed\u5473\uff0c\u982d\u6216\u984f\u9762\u75bc\u75db\u6216\u9178\uff0c\u54b3\u55fd\uff0c\u8033\u6735\u585e\u4f4f\uff0c\u5176\u5b83\u75c7\u72c0\uff0c\u5176\u5b83\u85e5\u7269<\/p>\n

\u75c7\u72c0\u4e4b\u586b\u5beb\u65b9\u5f0f:\u8acb\u586b0.1.2.3.4.5\uff1b \u5b8c\u5168\u7121\u6b64\u75c7\u72c0\u8acb\u586b:0\uff0c \u5076\u800c\u6709\u4e14\u5f88\u8f15\u5fae:1\uff0c \u8f15\u5fae:2\uff0c\u666e\u901a:3\uff0c\u56b4\u91cd:4\uff0c\u5f88\u56b4\u91cd: 5\uff0c\u9019\u662f\u5b8c\u5168\u6839\u64da\u60a8\u500b\u4eba\u7684\u4e3b\u89c0\u611f\u89ba\u4f86\u586b\u5beb\u3002<\/p>\n

\u8868\u4e8c \u5e74\u9f61\u5206\u4f48<\/p>\n

\u5e74\u9f61:
\n6-20 \u6b72: 10\u4eba
\n21-40 \u6b72: 6\u4eba
\n41-60 \u6b72: 6\u4eba
\n61-75 \u6b72: 1\u4eba<\/p>\n

*\u6027\u5225: \u7537\/\u5973= 10\/13(\u4eba)<\/p>\n

\u8868\u4e09 \u6cbb\u7642\u524d\u5f8c\u75c7\u72c0\u8b8a\u5316\u4e4b\u6bd4\u8f03(\u9032\u6b65 20\/23 (\u4eba) \u536087%)
\n[table id=5 \/]<\/p>\n

\u53c3\u8003\u91ab\u5b78\u6587\u737b: <\/p>\n

1. Grossan M.: A new nasal irrigator device. Eye Ear Nose Throat Mon 1974 Mar;53(3):87-90
\n2. Subiza JL, Subiza J, Barjau MC, et al: Inhibition of the seasonal IgE increase to Dactylis glomerata by daily sodium chloride nasal-sinus irrigation during the grass pollen season. J Allergy Clin Immunol 1999 Sep;104(3 Pt 1):711-2
\n3. Tomooka LT, Murphy C, Davidson TM. Clinical study and literature review of nasal irrigation. Laryngoscope 2000 Jul;110(7):1189-93
\n4. Zubizarreta PA, D’Antonio G, Raslawski E,et al: Nasopharyngeal carcinoma in childhood and adolescence: a single-institution experience with combined therapy. Cancer 2000 Aug 1;89(3):690-5
\n5. Chang CC, Chen MK, Wen YS,et al: Effects of radiotherapy for nasopharyngeal carcinoma on the paranasal sinuses: study based on computed tomography scanning. J Otolaryngol 2000 Feb;29(1):23-7
\n6. Porter MJ, Leung SF, Ambrose R,et al: The paranasal sinuses before and after radiotherapy for nasopharyngeal carcinoma: a computed tomographic study. J Laryngol Otol 1996 Jan;110(1):19-22
\n7. Weber R, Keerl R, Huppmann A,et al; Effects of postoperative care on wound healing after endonasal paranasal sinus surgery Laryngorhinootologie 1996 Apr;75(4):208-14
\n8. Don DM, Yellon RF, Casselbrant ML,et al: Efficacy of a stepwise protocol that includes intravenous antibiotic therapy for the management of chronic sinusitis in children and adolescents. Arch Otolaryngol Head Neck Surg 2001 Sep;127(9):1093-8
\n9. Orsini JA, Park MI, Spencer PA. Tissue and serum concentrations of amikacin after intramuscular and intrauterine administration to mares in estrus. Can Vet J 1996 Mar;37(3):157-60
\n10. Davidson TM, Murphy C, Mitchell M,et al: Management of chronic sinusitis in cystic fibrosis. Laryngoscope 1995 Apr;105(4 Pt 1):354-8
\n11. Ponikau JU, Sherris DA, Kern EB,et al: The diagnosis and incidence of allergic fungal sinusitis. Mayo Clin Proc 1999 Sep;74(9):877-84
\n12. Ricchetti A, Landis BN, Maffioli A,et al: Effect of anti-fungal nasal lavage with amphotericin B on nasal polyposis. J Laryngol Otol 2002 Apr;116(4):261-3
\n13. Hartog B, van Benthem PP, Prins LC,et al: Efficacy of sinus irrigation versus sinus irrigation followed by functional endoscopic sinus surgery. Ann Otol Rhinol Laryngol 1997 Sep;106(9):759-66
\n14. Rechtweg JS, Paolini RV, Belmont MJ,et al: Postoperative antibiotic use of septoplasty: a survey of practice habits of the membership of the American Rhinologic Society. Am J Rhinol 2001 Sep-Oct;15(5):315-20
\n15. \u859b\u667a\u4ec1 \u8a31\u5fd7\u5b8f \u6797\u6e05\u69ae\u9f3b\u54bd\u764c\u75c5\u4eba\u653e\u5c04\u6cbb\u7642\u5f8c\u4e4b\u9f3b\u7ac7\u8b8a\u5316\u4e2d\u83ef\u6c11\u570b\u8033\u9f3b\u5589\u79d1\u91ab\u5b78\u96dc\u8a8c 35:3 \u6c1189.05-06 \u9801162-167
\n16. Homer JJ, England RJ, Wilde AD,et al: The effect of pH of douching solutions on mucociliary clearance. Clin Otolaryngol 1999 Aug;24(4):312-5
\n17. Talbot AR, Herr TM, Parsons DS. Mucociliary clearance and buffered hypertonic saline solution. Laryngoscope 1997 Apr;107(4):500-3
\n18. Shoseyov D, Bibi H, Shai P,et al: Treatment with hypertonic saline versus normal saline nasal wash of pediatric chronic sinusitis. J Allergy Clin Immunol 1998 May;101(5):602-5
\n19. Bachmann G, Hommel G, Michel O. Effect of irrigation of the nose with isotonic salt solution on adult patients with chronic paranasal sinus disease. Eur Arch Otorhinolaryngol 2000 Dec;257(10):537-41
\n20. Keerl R, Weber R, Muller C,et al: Effectiveness and tolerance of nasal irrigation following paranasal sinus surgery Laryngorhinootologie 1997 Mar;76(3):137-41<\/p>\n

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